PhenoGenX – ML Resistance Analysis

Mutation-based machine learning predictions for HIV-1 drug resistance (POL region).

Unified Backend: http://127.0.0.1:5000
ML Backend: http://127.0.0.1:42360
Model Status
Ready
Awaiting file upload
Sequences
0
Total processed
Drugs
22
Available ML models
Last Run
–
Local time
Upload multiple FASTA files; each file may contain multiple sequences.
No files selected. Choose one or more FASTA files to begin.
Export Results

Exports are generated after a successful analysis run.

Upload a CSV file with format: Sample ID,Patient name,Mutation or similar.
Sample ID,Patient name,Mutation
1,John Doe,"M184V;K103N;L210W;T215Y"
2,Jane Smith,"M41L;L74I;M184V;L210W;T215Y"
3,Bob Johnson,"M184V;S68SG;L210W;T215Y"
Hold Ctrl/Cmd to select multiple drugs. Default: All drugs selected.
No mutation CSV selected. Upload a CSV file with mutation data.
Mutation Analysis Export

Export mutation analysis results after processing.

Mutation Filtering Rules

Drug-Class Specific Filtering (Display Only):

  • NRTI 3TC, ABC, AZT, D4T, DDI, TDF
  • NNRTI EFV, NVP, ETR, RPV
  • PI ATV, LPV, IDV, NFV, SQV, FPV, RTV, TPV
  • INSTI DTG, BIC, RAL, EVG

Note: ML predictions use ALL mutations. Display shows relevant mutations by drug class.

ML Resistance Predictions
No analysis yet
Select an analysis type above and run analysis to populate the table.
Sample/Sequence ID Type All Mutations Relevant Mutations Status
No data available. Run an analysis to see results.
Client Console
> PhenoGenX ML frontend initialized…
> Ready for FASTA file analysis
> Ready for Mutation CSV analysis